project what we will deliver

2024

Toolbox to detect abnormal gyration

2025

Publication on lesion-related brain connectivity impairment assessed from intracranial electrophysiology

First release of generic detector of abnormality ready

First simulation of brain network model with biophysical parameters and dopaminergic neuromodulation

2026

Validation of D1.1 outputs using FTRACT

Internal validation of the invariant Riemannian connectome model accomplished

Validation of metrics based on directed FC and EC that track patient-specific deviations from healthy trajectories

Validation of metrics based on dFC that track patient-specific deviations from healthy trajectories

Virtual cohorts of healthy and AD trajectories are validated against cross-sectional cohorts

Internal validation of Simulation-based generative modeling engine

Brain network model with biophysical parameters and dopaminergic neuromodulation

2027

Optimized tools to identify and characterize several lesion types, using several retrospective datasets

Software module for invariant connectivity learning of functional connectomes for phenotypic prediction (and associated publication)

Pipeline assessing individual Brain Health Status (BHS) using directed FC and EC for resting-state fMRI data (and associated publication)

Toolbox for dFC-based prediction of cognitive impairment evolution and reserve estimation (and associated publication)

Toolbox assessing BHS using Simulation-Based Inference (SBI)

Software module for 3D generative modeling of the brain